Anti-SRSF9 antibody [5A12] (STJA0032740)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2b
ImmunogenFull length human recombinant protein of human SRSF9 produced in E.coli.
General Information
| Short Description | Mouse monoclonal anti-SRSF9 for use in WB and IHC-P in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P |
| Host | Mouse |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 5A12 |
| Isotype | IgG2b |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100 |
| Formulation | Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | SRSF9 |
| Gene ID | 8683 |
| Uniprot ID | SRSF9_HUMAN |
| Immunogen | Full length human recombinant protein of human SRSF9 produced in E.coli. |
Additional Info
| Tissue Specificity | Expressed at high levels in the heart, kidney, pancreas and placenta, and at lower levels in the brain, liver, lung and skeletal muscle. |
| Post Translational Modifications | Extensively phosphorylated on serine residues in the RS domain. |
| Function | Plays a role in constitutive splicing and can modulate the selection of alternative splice sites. Represses the splicing of MAPT/Tau exon 10. |
| Protein Name | Serine/Arginine-Rich Splicing Factor 9Pre-Mrna-Splicing Factor Srp30cSplicing Factor - Arginine/Serine-Rich 9 |
| Database Links | Reactome: R-HSA-159236Reactome: R-HSA-72163Reactome: R-HSA-72187Reactome: R-HSA-72203Reactome: R-HSA-73856 |
| Cellular Localisation | NucleusCellular Stresses Such As Heat Shock May Induce Localization To Discrete Nuclear Bodies Termed Sam68 Nuclear Bodies (Snbs)Hap BodiesOr Stress BodiesNumerous Splicing Factors Including Srsf1/Sfrs1/Sf2Srsf7/Sfrs7Safb And Khdrbs1/Sam68 Accumulate At These StructuresWhich May Participate In The Post-Transcriptional Regulation Of Mrnas In Stressed Cells |
| Alternative Antibody Names | Anti-Serine/Arginine-Rich Splicing Factor 9 antibodyAnti-Pre-Mrna-Splicing Factor Srp30c antibodyAnti-Splicing Factor - Arginine/Serine-Rich 9 antibodyAnti-SRSF9 antibodyAnti-SFRS9 antibodyAnti-SRP30C antibody |
Information sourced from Uniprot.org