Anti-SRSF9 antibody [5A12] (STJA0032740)

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STJA0032740
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Short Description :Mouse monoclonal anti-SRSF9 for use in WB and IHC-P in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IHC-P
Host:Mouse
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :5A12
Isotype:IgG2b
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:Affinity Purified
Dilution Range:WB 1:500-1:1000
IHC 1:50-1:100
Formulation:Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3.
Storage Instruction:Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol:SRSF9
Gene ID:8683
Uniprot ID:SRSF9_HUMAN
Immunogen:Full length human recombinant protein of human SRSF9 produced in E.coli.
Tissue Specificity Expressed at high levels in the heart, kidney, pancreas and placenta, and at lower levels in the brain, liver, lung and skeletal muscle.
Post Translational Modifications Extensively phosphorylated on serine residues in the RS domain.
Function Plays a role in constitutive splicing and can modulate the selection of alternative splice sites. Represses the splicing of MAPT/Tau exon 10.
Protein Name Serine/Arginine-Rich Splicing Factor 9
Pre-Mrna-Splicing Factor Srp30c
Splicing Factor - Arginine/Serine-Rich 9
Database Links Reactome: R-HSA-159236
Reactome: R-HSA-72163
Reactome: R-HSA-72187
Reactome: R-HSA-72203
Reactome: R-HSA-73856
Cellular Localisation Nucleus
Cellular Stresses Such As Heat Shock May Induce Localization To Discrete Nuclear Bodies Termed Sam68 Nuclear Bodies (Snbs)
Hap Bodies
Or Stress Bodies
Numerous Splicing Factors Including Srsf1/Sfrs1/Sf2
Srsf7/Sfrs7
Safb And Khdrbs1/Sam68 Accumulate At These Structures
Which May Participate In The Post-Transcriptional Regulation Of Mrnas In Stressed Cells
Alternative Antibody Names Anti-Serine/Arginine-Rich Splicing Factor 9 antibody
Anti-Pre-Mrna-Splicing Factor Srp30c antibody
Anti-Splicing Factor - Arginine/Serine-Rich 9 antibody
Anti-SRSF9 antibody
Anti-SFRS9 antibody
Anti-SRP30C antibody

Information sourced from Uniprot.org