Anti-SRSF7 antibody (60-120) (STJ119149)

Name: Anti-SRSF7 antibody (60-120) (STJ119149)
SKU: STJ119149
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ119149

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Short Description	Rabbit polyclonal SRSF7 (60-120) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC-P/IF/ICC/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:1000 IHC-P:1:50-1:200 IF/ICC:1:50-1:100 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	SRSF7
Gene ID	6432
Uniprot ID	SRSF7_HUMAN
Immunogen Region	60-120
Immunogen Sequence	AEDAVRGLDGKVICGSRVRV ELSTGMPRRSRFDRPPARRP FDPNDRCYECGEKGHYAYDC H
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 60-120 of human SRSF7 (NP_001026854).

Tissue Specificity	Brain, liver, kidney and lung.
Post Translational Modifications	Extensively phosphorylated on serine residues in the RS domain.
Function	Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon 10. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway).enhances NXF1-NXT1 RNA-binding activity. RNA-binding is semi-sequence specific.
Protein Name	Serine/Arginine-Rich Splicing Factor 7 Splicing Factor 9g8 Splicing Factor - Arginine/Serine-Rich 7
Database Links	Reactome: R-HSA-159236 Reactome: R-HSA-72163 Reactome: R-HSA-72165 Reactome: R-HSA-72187 Reactome: R-HSA-72203 Reactome: R-HSA-73856
Cellular Localisation	Nucleus Cytoplasm
Alternative Antibody Names	Anti-Serine/Arginine-Rich Splicing Factor 7 antibody Anti-Splicing Factor 9g8 antibody Anti-Splicing Factor - Arginine/Serine-Rich 7 antibody Anti-SRSF7 antibody Anti-SFRS7 antibody

Information sourced from Uniprot.org