Anti-SRPX2 antibody (430-470) (STJ503134)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide taken within amino acid region 430-470 on human SRPX2 protein.
General Information
| Short Description | Rabbit polyclonal antibody anti-SRPX2 (430-470) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Applications | ELISA/IHC/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.55-0.75 µg/µl |
| Purification | Affinity Purified |
| Dilution Range | WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:100IHC: 1:200 |
| Formulation | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | SRPX2 |
| Gene ID | 27286 |
| Uniprot ID | SRPX2_HUMAN |
| Immunogen | Synthetic peptide taken within amino acid region 430-470 on human SRPX2 protein. |
| Immunogen Region | 430-470 |
Additional Info
| Tissue Specificity | Expressed in neurons of the rolandic area of the brain (at protein level). Highly expressed in the brain, placenta, lung, trachea, uterus, adrenal gland, heart, ovary and placenta. Weakly expressed in the peripheral blood, brain and bone marrow. Expressed in numerous cancer cell lines and in gastrointestinal cancer cells. Higher levels found in colorectal cancers than in normal colonic mucosa. |
| Post Translational Modifications | Contains chondroitin sulfate chains. |
| Function | Acts as a ligand for the urokinase plasminogen activator surface receptor. Plays a role in angiogenesis by inducing endothelial cell migration and the formation of vascular network (cords). Involved in cellular migration and adhesion. Increases the phosphorylation levels of FAK. Interacts with and increases the mitogenic activity of HGF. Promotes synapse formation. May have a role in the perisylvian region, critical for language and cognitive development. |
| Protein Name | Sushi Repeat-Containing Protein Srpx2Sushi-Repeat Protein Upregulated In Leukemia |
| Cellular Localisation | SecretedCytoplasmCell SurfaceSynapse |
| Alternative Antibody Names | Anti-Sushi Repeat-Containing Protein Srpx2 antibodyAnti-Sushi-Repeat Protein Upregulated In Leukemia antibodyAnti-SRPX2 antibodyAnti-SRPUL antibody |
Information sourced from Uniprot.org