Anti-SRP19 antibody (1-144) (STJ28835)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SRP19 (1-144) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SRP19 |
| Gene ID | 6728 |
| Uniprot ID | SRP19_HUMAN |
| Immunogen Region | 1-144 |
| Immunogen Sequence | MACAAARSPADQDRFICIYP AYLNNKKTIAEGRRIPISKA VENPTATEIQDVCSAVGLNV FLEKNKMYSREWNRDVQYRG RVRVQLKQEDGSLCLVQFPS RKSVMLYAAEMIPKLKTRTQ KTGGADQSLQQGEGSKKGKG KKKK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-144 of human SRP19 (NP_003126.1). |
Additional Info
| Function | Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). Binds directly to 7SL RNA. Mediates binding of SRP54 to the SRP complex. |
| Protein Name | Signal Recognition Particle 19 Kda ProteinSrp19 |
| Database Links | Reactome: R-HSA-1799339 |
| Cellular Localisation | CytoplasmNucleusNucleolusNucleoplasmAlthough The Signal Recognition Particle Complex Acts In The CytoplasmIt Assembles At Least In Part In The Nucleus And/Or The NucleolusSrp19 Nuclear Import May Be Mediated By Ipo8/Imp8 And Tpno1/Trn |
| Alternative Antibody Names | Anti-Signal Recognition Particle 19 Kda Protein antibodyAnti-Srp19 antibodyAnti-SRP19 antibody |
Information sourced from Uniprot.org