Anti-SRP19 antibody (1-144) (STJ28835)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJ28835
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General Information

Short DescriptionRabbit polyclonal SRP19 (1-144) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IHC-P/ELISA
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB:1:500-1:2000
IHC-P:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
FormulationPBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage InstructionStore at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolSRP19
Gene ID6728
Uniprot IDSRP19_HUMAN
Immunogen Region1-144
Immunogen SequenceMACAAARSPADQDRFICIYP AYLNNKKTIAEGRRIPISKA VENPTATEIQDVCSAVGLNV FLEKNKMYSREWNRDVQYRG RVRVQLKQEDGSLCLVQFPS RKSVMLYAAEMIPKLKTRTQ KTGGADQSLQQGEGSKKGKG KKKK
SpecificityRecombinant fusion protein containing a sequence corresponding to amino acids 1-144 of human SRP19 (NP_003126.1).

Additional Info

Function Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). Binds directly to 7SL RNA. Mediates binding of SRP54 to the SRP complex.
Protein Name Signal Recognition Particle 19 Kda Protein
Srp19
Database Links Reactome: R-HSA-1799339
Cellular Localisation Cytoplasm
Nucleus
Nucleolus
Nucleoplasm
Although The Signal Recognition Particle Complex Acts In The Cytoplasm
It Assembles At Least In Part In The Nucleus And/Or The Nucleolus
Srp19 Nuclear Import May Be Mediated By Ipo8/Imp8 And Tpno1/Trn
Alternative Antibody Names Anti-Signal Recognition Particle 19 Kda Protein antibody
Anti-Srp19 antibody
Anti-SRP19 antibody

Information sourced from Uniprot.org

Citations

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