Anti-SRGAP1 antibody (159-209 aa) (STJ195524)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human SRGP1 at the amino acid range 159-209
General Information
| Short Description | Rabbit polyclonal anti-SLIT-ROBO Rho GTPase-activating protein 1 (159-209 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SRGAP1 |
| Gene ID | 57522 |
| Uniprot ID | SRGP1_HUMAN |
| Immunogen | Synthesized peptide derived from the human SRGP1 at the amino acid range 159-209 |
| Immunogen Region | 159-209 aa |
| Specificity | This antibody detects endogenous levels of SRGP1 at Human/Mouse |
Additional Info
| Function | GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42 seems to be involved in the pathway mediating the repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably through interaction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42. |
| Protein Name | Slit-Robo Rho Gtpase-Activating Protein 1Srgap1Rho Gtpase-Activating Protein 13 |
| Database Links | Reactome: R-HSA-428543Reactome: R-HSA-8980692Reactome: R-HSA-9013148Reactome: R-HSA-9013149 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Slit-Robo Rho Gtpase-Activating Protein 1 antibodyAnti-Srgap1 antibodyAnti-Rho Gtpase-Activating Protein 13 antibodyAnti-SRGAP1 antibodyAnti-ARHGAP13 antibodyAnti-KIAA1304 antibody |
Information sourced from Uniprot.org