Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-SLIT-ROBO Rho GTPase-activating protein 1 (159-209 aa) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
SRGAP1 |
Gene ID: |
57522 |
Uniprot ID: |
SRGP1_HUMAN |
Immunogen Region: |
159-209 aa |
Specificity: |
This antibody detects endogenous levels of SRGP1 at Human/Mouse |
Immunogen: |
Synthesized peptide derived from the human SRGP1 at the amino acid range 159-209 |
Function | GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42 seems to be involved in the pathway mediating the repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably through interaction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42. |
Protein Name | Slit-Robo Rho Gtpase-Activating Protein 1Srgap1Rho Gtpase-Activating Protein 13 |
Database Links | Reactome: R-HSA-428543Reactome: R-HSA-8980692Reactome: R-HSA-9013148Reactome: R-HSA-9013149 |
Alternative Antibody Names | Anti-Slit-Robo Rho Gtpase-Activating Protein 1 antibodyAnti-Srgap1 antibodyAnti-Rho Gtpase-Activating Protein 13 antibodyAnti-SRGAP1 antibodyAnti-ARHGAP13 antibodyAnti-KIAA1304 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance