Anti-SRD5A2 antibody (190-250 aa) (STJ13102127)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from aa region 190-250 of human SRD5A2 conjugated to blue carrier protein was used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-SRD5A2 (190-250 aa) for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1: 4000 is recommended for WB and 1: 2000 for IHC-P. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | SRD5A2 |
| Gene ID | 6716 |
| Uniprot ID | S5A2_HUMAN |
| Immunogen | A synthetic peptide from aa region 190-250 of human SRD5A2 conjugated to blue carrier protein was used as the antigen. |
| Immunogen Region | 190-250 aa |
| Specificity | Specific for SRD5A2. |
Additional Info
| Function | Converts testosterone (T) into 5-alpha-dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology. |
| Protein Name | 3-Oxo-5-Alpha-Steroid 4-Dehydrogenase 25 Alpha-Sr2Sr Type 2Steroid 5-Alpha-Reductase 2S5ar 2Type Ii 5-Alpha Reductase |
| Database Links | Reactome: R-HSA-193048 |
| Cellular Localisation | Microsome MembraneMulti-Pass Membrane ProteinEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-3-Oxo-5-Alpha-Steroid 4-Dehydrogenase 2 antibodyAnti-5 Alpha-Sr2 antibodyAnti-Sr Type 2 antibodyAnti-Steroid 5-Alpha-Reductase 2 antibodyAnti-S5ar 2 antibodyAnti-Type Ii 5-Alpha Reductase antibodyAnti-SRD5A2 antibody |
Information sourced from Uniprot.org