Anti-SPTBN1 antibody [PT0426R] (STJA0039501)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgGk
General Information
| Short Description | Rabbit monoclonal anti-Spectrin Beta Chain-Non-Erythrocytic 1 for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | PT0426R |
| Isotype | IgGk |
| Conjugation | Unconjugated |
| Purification | Protein A |
| Dilution Range | IHC 1:1000-1:5000WB 1:2000-1:10000IF 1:200-1:1000ELISA 1:5000-1:20000 |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SPTBN1 |
| Gene ID | 6711 |
| Uniprot ID | SPTB2_HUMAN |
| Specificity | Endogenous |
Additional Info
| Function | Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane. Plays a critical role in central nervous system development and function. |
| Protein Name | Spectrin Beta Chain - Non-Erythrocytic 1Beta-Ii SpectrinFodrin Beta ChainSpectrin - Non-Erythroid Beta Chain 1 |
| Database Links | Reactome: R-HSA-373753Reactome: R-HSA-375165Reactome: R-HSA-445095Reactome: R-HSA-5673001Reactome: R-HSA-6807878Reactome: R-HSA-9013420Reactome: R-HSA-9013424Reactome: R-HSA-9662360Reactome: R-HSA-9662361Reactome: R-HSA-9703465 |
| Cellular Localisation | CytoplasmCytoskeletonMyofibrilSarcomereM LineCytosolCell MembraneColocalizes With Ank2 In A Distinct Intracellular Compartment Of Neonatal CardiomyocytesIsoform 2: Cell MembranePeripheral Membrane ProteinCytoplasmic Side |
| Alternative Antibody Names | Anti-Spectrin Beta Chain - Non-Erythrocytic 1 antibodyAnti-Beta-Ii Spectrin antibodyAnti-Fodrin Beta Chain antibodyAnti-Spectrin - Non-Erythroid Beta Chain 1 antibodyAnti-SPTBN1 antibodyAnti-SPTB2 antibody |
Information sourced from Uniprot.org