Anti-SPRR1B antibody (STJA0008476)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human SPRR1B
General Information
| Short Description | Rabbit polyclonal anti-Cornifin-B for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SPRR1B |
| Gene ID | 6699 |
| Uniprot ID | SPR1B_HUMAN |
| Immunogen | Synthesized peptide derived from human SPRR1B |
| Specificity | This antibody detects endogenous levels of SPRR1B at Human, Mouse |
Additional Info
| Post Translational Modifications | The N-terminus is blocked. |
| Function | Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both amine donor and acceptor in transglutaminase-mediated cross-linkage. |
| Protein Name | Cornifin-B14.9 Kda PancornulinSmall Proline-Rich Protein IbSpr-Ib |
| Database Links | Reactome: R-HSA-6809371 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Cornifin-B antibodyAnti-14.9 Kda Pancornulin antibodyAnti-Small Proline-Rich Protein Ib antibodyAnti-Spr-Ib antibodyAnti-SPRR1B antibody |
Information sourced from Uniprot.org