Anti-SPR antibody (1-261) (STJ113293)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SPR (1-261) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SPR |
| Gene ID | 6697 |
| Uniprot ID | SPRE_HUMAN |
| Immunogen Region | 1-261 |
| Immunogen Sequence | MEGGLGRAVCLLTGASRGFG RTLAPLLASLLSPGSVLVLS ARNDEALRQLEAELGAERSG LRVVRVPADLGAEAGLQQLL GALRELPRPKGLQRLLLINN AGSLGDVSKGFVDLSDSTQV NNYWALNLTSMLCLTSSVLK AFPDSPGLNRTVVNISSLCA LQPFKGWALYCAGKAARDML FQVLALEEPNVRVLNYAPGP LDTDMQQLARETSVDPDMRK GLQELKAKGKLVDCKVSAQ |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-261 of human SPR (NP_003115.1). |
Additional Info
| Post Translational Modifications | In vitro phosphorylation of Ser-213 by CaMK2 does not change kinetic parameters. |
| Function | Catalyzes the final one or two reductions in tetra-hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin. |
| Protein Name | Sepiapterin ReductaseSpr |
| Database Links | Reactome: R-HSA-1474151Reactome: R-HSA-203615 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Sepiapterin Reductase antibodyAnti-Spr antibodyAnti-SPR antibody |
Information sourced from Uniprot.org