Anti-SPON2 antibody (Internal) (STJ72721)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-SPON2 (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/WB/IHC |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx 35-36kDa band observed in Human, Mouse and Rat Kidney lysates, and in preliminary testing of A549 cell lysates (calculated MW of 35.8kDa according to Human NP_036577.2, and 36.0 |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | SPON2 |
| Gene ID | 10417 |
| Uniprot ID | SPON2_HUMAN |
| Accession Number | NP_036577.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | RTRYVRVQPANNGSP |
| Specificity | Reported variants represent identical protein: NP_036577.1, NP_001121797.1, NP_001185950.1 |
Additional Info
| Function | Cell adhesion protein that promotes adhesion and outgrowth of hippocampal embryonic neurons. Binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria. Essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the ECM for microbial pathogens. Binds bacterial lipopolysaccharide (LPS). |
| Protein Name | Spondin-2Differentially Expressed In Cancerous And Non-Cancerous Lung Cells 1Dil-1Mindin |
| Database Links | Reactome: R-HSA-5083635Reactome: R-HSA-5173214 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Spondin-2 antibodyAnti-Differentially Expressed In Cancerous And Non-Cancerous Lung Cells 1 antibodyAnti-Dil-1 antibodyAnti-Mindin antibodyAnti-SPON2 antibodyAnti-DIL1 antibodyAnti-UNQ435 antibodyAnti-PRO866 antibody |
Information sourced from Uniprot.org