| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SPON2 (27-150) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000IHC-P 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SPON2 |
| Gene ID: |
10417 |
| Uniprot ID: |
SPON2_HUMAN |
| Immunogen Region: |
27-150 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 27-150 of human SPON2 (NP_036577.1). |
| Immunogen Sequence: |
QPLGGESICSARAPAKYSIT FTGKWSQTAFPKQYPLFRPP AQWSSLLGAAHSSDYSMWRK NQYVSNGLRDFAERGEAWAL MKEIEAAGEALQSVHAVFSA PAVPSGTGQTSAELEVQRRH SLVS |
| Tissue Specificity | Expressed in normal lung tissue but not in lung carcinoma cell lines. |
| Function | Cell adhesion protein that promotes adhesion and outgrowth of hippocampal embryonic neurons. Binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria. Essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the ECM for microbial pathogens. Binds bacterial lipopolysaccharide (LPS). |
| Protein Name | Spondin-2Differentially Expressed In Cancerous And Non-Cancerous Lung Cells 1Dil-1Mindin |
| Database Links | Reactome: R-HSA-5083635Reactome: R-HSA-5173214 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Spondin-2 antibodyAnti-Differentially Expressed In Cancerous And Non-Cancerous Lung Cells 1 antibodyAnti-Dil-1 antibodyAnti-Mindin antibodyAnti-SPON2 antibodyAnti-DIL1 antibodyAnti-UNQ435 antibodyAnti-PRO866 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and BMPR2 knockout (KO) HeLa cells, using [KO Validated] BMPR2 Rabbit polyclonal antibody (STJ11100052) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/89123/357574/STJ11100052_1__66941.1713121704.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and BMPR2 knockout (KO) HeLa cells, using [KO Validated] BMPR2 Rabbit polyclonal antibody (STJ11100052) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.")