Anti-SPON2 antibody (27-150) (STJ113975)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SPON2 (27-150) antibody for use in WB, IHC-P and ELISA in human and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SPON2 |
| Gene ID | 10417 |
| Uniprot ID | SPON2_HUMAN |
| Immunogen Region | 27-150 |
| Immunogen Sequence | QPLGGESICSARAPAKYSIT FTGKWSQTAFPKQYPLFRPP AQWSSLLGAAHSSDYSMWRK NQYVSNGLRDFAERGEAWAL MKEIEAAGEALQSVHAVFSA PAVPSGTGQTSAELEVQRRH SLVS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 27-150 of human SPON2 (NP_036577.1). |
Additional Info
| Tissue Specificity | Expressed in normal lung tissue but not in lung carcinoma cell lines. |
| Function | Cell adhesion protein that promotes adhesion and outgrowth of hippocampal embryonic neurons. Binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria. Essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the ECM for microbial pathogens. Binds bacterial lipopolysaccharide (LPS). |
| Protein Name | Spondin-2Differentially Expressed In Cancerous And Non-Cancerous Lung Cells 1Dil-1Mindin |
| Database Links | Reactome: R-HSA-5083635Reactome: R-HSA-5173214 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Spondin-2 antibodyAnti-Differentially Expressed In Cancerous And Non-Cancerous Lung Cells 1 antibodyAnti-Dil-1 antibodyAnti-Mindin antibodyAnti-SPON2 antibodyAnti-DIL1 antibodyAnti-UNQ435 antibodyAnti-PRO866 antibody |
Information sourced from Uniprot.org