Anti-SPOCK3 antibody (180-380) (STJ114715)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SPOCK3 (180-380) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SPOCK3 |
| Gene ID | 50859 |
| Uniprot ID | TICN3_HUMAN |
| Immunogen Region | 180-380 |
| Immunogen Sequence | CPCPSDKPTSTSRNVKRACS DLEFREVANRLRDWFKALHE SGSQNKKTKTLLRPERSRFD TSILPICKDSLGWMFNRLDT NYDLLLDQSELRSIYLDKNE QCTKAFFNSCDTYKDSLISN NEWCYCFQRQQDPPCQTELS NIQKRQGVKKLLGQYIPLCD EDGYYKPTQCHGSVGQCWCV DRYGNEVMGSRINGVADCAI D |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 180-380 of human SPOCK3 (NP_001035249.1). |
Additional Info
| Tissue Specificity | Expressed in brain. |
| Post Translational Modifications | Contains chondroitin sulfate and heparan sulfate O-linked oligosaccharides. |
| Function | May participate in diverse steps of neurogenesis. Inhibits the processing of pro-matrix metalloproteinase 2 (MMP-2) by MT1-MMP and MT3-MMP. May interfere with tumor invasion. |
| Protein Name | Testican-3Sparc/Osteonectin - Cwcv - And Kazal-Like Domains Proteoglycan 3 |
| Database Links | Reactome: R-HSA-1592389 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Testican-3 antibodyAnti-Sparc/Osteonectin - Cwcv - And Kazal-Like Domains Proteoglycan 3 antibodyAnti-SPOCK3 antibodyAnti-TICN3 antibodyAnti-UNQ409 antibodyAnti-PRO771 antibody |
Information sourced from Uniprot.org