Anti-splicing factor 1 antibody [7D9E3] (STJ16103541)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2b
ImmunogenE. coli-derived human splicing factor 1 recombinant protein (Position: R160-Q266).
General Information
| Short Description | Mouse monoclonal anti-splicing factor 1 for use in WB, IHC, ICC, IF and FC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/ICC/IF/FC |
| Host | Mouse |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 7D9E3 |
| Isotype | IgG2b |
| Conjugation | Unconjugated |
| Concentration | Adding 0.2 mL of distilled water =f 500 Mu g/mL. |
| Purification | Lyophilized |
| Formulation | Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. NA |
| Storage Instruction | Store at-20ยฐC for up to 1 year. Minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | SF1 |
| Gene ID | 7536 |
| Uniprot ID | SF01_HUMAN |
| Immunogen | E. coli-derived human splicing factor 1 recombinant protein (Position: R160-Q266). |
Additional Info
| Post Translational Modifications | Phosphorylation on Ser-20 interferes with U2AF2 binding and spliceosome assembly. Isoform 6 is phosphorylated on Ser-463. |
| Function | Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor. |
| Protein Name | Splicing Factor 1Mammalian Branch Point-Binding ProteinBbpMbbpTranscription Factor Zfm1Zinc Finger Gene In Men1 LocusZinc Finger Protein 162 |
| Database Links | Reactome: R-HSA-72163 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Splicing Factor 1 antibodyAnti-Mammalian Branch Point-Binding Protein antibodyAnti-Bbp antibodyAnti-Mbbp antibodyAnti-Transcription Factor Zfm1 antibodyAnti-Zinc Finger Gene In Men1 Locus antibodyAnti-Zinc Finger Protein 162 antibodyAnti-SF1 antibodyAnti-ZFM1 antibodyAnti-ZNF162 antibody |
Information sourced from Uniprot.org