Anti-splicing factor 1 antibody [2F5D10] (STJ16103542)

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STJ16103542-100
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Short Description :Mouse monoclonal anti-splicing factor 1 for use in WB, IHC, ICC, IF and FC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IHC/ICC/IF/FC
Host:Mouse
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :2F5D10
Isotype:IgG2a
Conjugation:Unconjugated
Concentration:Adding 0.2 mL of distilled water =f 500 Mu g/mL.
Purification:Lyophilized
Formulation:Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. NA
Storage Instruction:Store at-20°C for up to 1 year. Minimise freeze-thaw cycles.
Gene Symbol:SF1
Gene ID:7536
Uniprot ID:SF01_HUMAN
Immunogen:E. coli-derived human splicing factor 1 recombinant protein (Position: R160-Q266).
Post Translational Modifications Phosphorylation on Ser-20 interferes with U2AF2 binding and spliceosome assembly. Isoform 6 is phosphorylated on Ser-463.
Function Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor.
Protein Name Splicing Factor 1
Mammalian Branch Point-Binding Protein
Bbp
Mbbp
Transcription Factor Zfm1
Zinc Finger Gene In Men1 Locus
Zinc Finger Protein 162
Database Links Reactome: R-HSA-72163
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Splicing Factor 1 antibody
Anti-Mammalian Branch Point-Binding Protein antibody
Anti-Bbp antibody
Anti-Mbbp antibody
Anti-Transcription Factor Zfm1 antibody
Anti-Zinc Finger Gene In Men1 Locus antibody
Anti-Zinc Finger Protein 162 antibody
Anti-SF1 antibody
Anti-ZFM1 antibody
Anti-ZNF162 antibody

Information sourced from Uniprot.org