Anti-SPINT2 antibody (Internal) (STJ72323)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-SPINT2 (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/WB/IHC |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx 19kDa band observed in Human Placenta lysates (calculated MW of 21.8kDa according to NP_001159575.1). Recommended concentration: 0.3-1µg/ml. Primary incubation was 1 hour.I |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | SPINT2 |
| Gene ID | 10653 |
| Uniprot ID | SPIT2_HUMAN |
| Accession Number | NP_066925.1; NP_001159575.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | PSAPRRQDSEDH |
| Specificity | This antibody is expected to recognize both reported isoforms (NP_066925.1; NP_001159575.1). |
Additional Info
| Function | Inhibitor of HGFAC. Also inhibits plasmin, and plasma and tissue kallikrein. Inhibits serine protease activity of TMPRSS13. Inhibits serine protease activity of ST14/matriptase and PRSS8/prostasin in vitro. |
| Protein Name | Kunitz-Type Protease Inhibitor 2Hepatocyte Growth Factor Activator Inhibitor Type 2Hai-2Placental Bikunin |
| Database Links | Reactome: R-HSA-6806942Reactome: R-HSA-8852405 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCytoplasm |
| Alternative Antibody Names | Anti-Kunitz-Type Protease Inhibitor 2 antibodyAnti-Hepatocyte Growth Factor Activator Inhibitor Type 2 antibodyAnti-Hai-2 antibodyAnti-Placental Bikunin antibodyAnti-SPINT2 antibodyAnti-HAI2 antibodyAnti-KOP antibody |
Information sourced from Uniprot.org