Anti-SPINT2 antibody (28-197) (STJ28832)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SPINT2 (28-197) antibody for use in WB, IF, ICC and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SPINT2 |
| Gene ID | 10653 |
| Uniprot ID | SPIT2_HUMAN |
| Immunogen Region | 28-197 |
| Immunogen Sequence | ADRERSIHDFCLVSKVVGRC RASMPRWWYNVTDGSCQLFV YGGCDGNSNNYLTKEECLKK CATVTENATGDLATSRNAAD SSVPSAPRRQDSEDHSSDMF NYEEYCTANAVTGPCRASFP RWYFDVERNSCNNFIYGGCR GNKNSYRSEEACMLRCFRQQ ENPPLPLGSK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 28-197 of human SPINT2 (NP_066925.1). |
Additional Info
| Tissue Specificity | Expressed in placenta, kidney, pancreas, prostate, testis, thymus, and trachea. |
| Function | Inhibitor of HGFAC. Also inhibits plasmin, and plasma and tissue kallikrein. Inhibits serine protease activity of TMPRSS13. Inhibits serine protease activity of ST14/matriptase and PRSS8/prostasin in vitro. |
| Protein Name | Kunitz-Type Protease Inhibitor 2Hepatocyte Growth Factor Activator Inhibitor Type 2Hai-2Placental Bikunin |
| Database Links | Reactome: R-HSA-6806942Reactome: R-HSA-8852405 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCytoplasm |
| Alternative Antibody Names | Anti-Kunitz-Type Protease Inhibitor 2 antibodyAnti-Hepatocyte Growth Factor Activator Inhibitor Type 2 antibodyAnti-Hai-2 antibodyAnti-Placental Bikunin antibodyAnti-SPINT2 antibodyAnti-HAI2 antibodyAnti-KOP antibody |
Information sourced from Uniprot.org