| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Speedy protein A is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SPDYA |
| Gene ID: |
245711 |
| Uniprot ID: |
SPDYA_HUMAN |
| Specificity: |
This antibody detects endogenous levels of SPDYA at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human SPDYA |
| Function | Regulates the G1/S phase transition of the cell cycle by binding and activating CDK1 and CDK2. Contributes to CDK2 activation without promoting CDK2 phosphorylation, by inducing a conformation change of the CDK2 T-loop that obstructs the substrate-binding cleft prior to kinase activation. Mediates cell survival during the DNA damage process through activation of CDK2. |
| Protein Name | Speedy Protein ARapid Inducer Of G2/M Progression In Oocytes ARingo AHspy/Ringo ASpeedy-1Spy1 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Speedy Protein A antibodyAnti-Rapid Inducer Of G2/M Progression In Oocytes A antibodyAnti-Ringo A antibodyAnti-Hspy/Ringo A antibodyAnti-Speedy-1 antibodyAnti-Spy1 antibodyAnti-SPDYA antibodyAnti-SPDY1 antibodyAnti-SPY1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
