Anti-SPAM1 antibody [PT0768R] (STJA0039329)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgGk
General Information
| Short Description | Rabbit monoclonal anti-Hyaluronidase Ph-20 for use in WB and IHC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | PT0768R |
| Isotype | IgGk |
| Conjugation | Unconjugated |
| Purification | Protein A |
| Dilution Range | WB 1:1000-5000IHC 1:100-300 |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SPAM1 |
| Gene ID | 6677 |
| Uniprot ID | HYALP_HUMAN |
| Specificity | Endogenous |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Involved in sperm-egg adhesion. Upon fertilization sperm must first penetrate a layer of cumulus cells that surrounds the egg before reaching the zona pellucida. The cumulus cells are embedded in a matrix containing hyaluronic acid which is formed prior to ovulation. This protein aids in penetrating the layer of cumulus cells by digesting hyaluronic acid. |
| Protein Name | Hyaluronidase Ph-20Hyal-Ph20Hyaluronoglucosaminidase Ph-20Sperm Adhesion Molecule 1Sperm Surface Protein Ph-20 |
| Database Links | Reactome: R-HSA-2534343 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Antibody Names | Anti-Hyaluronidase Ph-20 antibodyAnti-Hyal-Ph20 antibodyAnti-Hyaluronoglucosaminidase Ph-20 antibodyAnti-Sperm Adhesion Molecule 1 antibodyAnti-Sperm Surface Protein Ph-20 antibodyAnti-SPAM1 antibodyAnti-HYAL3 antibodyAnti-PH20 antibody |
Information sourced from Uniprot.org