| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SPAG16 (1-183) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SPAG16 |
| Gene ID: |
79582 |
| Uniprot ID: |
SPG16_HUMAN |
| Immunogen Region: |
1-183 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-183 of human SPAG16 (NP_001020607.1). |
| Immunogen Sequence: |
MAAQRGMPSSAVRVLEEALG MGLTAAGDARDTADAVAAEG AYYLEQVTITEASEDDYEYE EIPDDNFSIPEGEEDLAKAI QMAQEQATDTEILERKTVLP SKHAVPEVIEDFLCNFLIKM GMTRTLDCFQSEWYELIQKG VTELRTVGNVPDVYTQIMLL ENENKNLKKDLKHYKQAAEY VIF |
| Tissue Specificity | Isoform 1 is detected in testis. Isoform 4 is detected in testis and brain, and at lower levels in kidney, heart, pancreas, thyroid, ovary, adrenal gland, spinal cord, trachea and liver. |
| Post Translational Modifications | Phosphorylated by TSSK2. |
| Function | Necessary for sperm flagellar function. Plays a role in motile ciliogenesis. May help to recruit STK36 to the cilium or apical surface of the cell to initiate subsequent steps of construction of the central pair apparatus of motile cilia. |
| Protein Name | Sperm-Associated Antigen 16 ProteinPf20 Protein Homolog |
| Cellular Localisation | CytoplasmCytoskeletonFlagellum AxonemeCilium AxonemeCell ProjectionCiliumFlagellumDetected On The Sperm Flagellum AxonemeDetected In The Central Apparatus Of The AxonemeColocalizes With Spag6 On Microtubules |
| Alternative Antibody Names | Anti-Sperm-Associated Antigen 16 Protein antibodyAnti-Pf20 Protein Homolog antibodyAnti-SPAG16 antibodyAnti-PF20 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
