• STJ70500 staining (1µg/ml) of Human EBV-immortilized lymphoblastoid lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Anti-SPA1/SIPA1 antibody (C-Term) (STJ70500)

SKU:
STJ70500-100

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Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-SPA1/SIPA1 (C-Term) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: ELISA-antibody detection limit dilution 1:32000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: SIPA1
Gene ID: 6494
Uniprot ID: SIPA1_HUMAN
Immunogen Region: C-Term
Accession Number: NP_694985.28; NP_006738.3
Specificity: Both variants represent identical protein (NP_694985.28 and NP_006738.3).
Immunogen Sequence: ASKQLGSPTADLA
Function GTPase activator for the nuclear Ras-related regulatory proteins Rap1 and Rap2 in vitro, converting them to the putatively inactive GDP-bound state. Affects cell cycle progression.
Protein Name Signal-Induced Proliferation-Associated Protein 1
Sipa-1
Gtpase-Activating Protein Spa-1
P130 Spa-1
Database Links Reactome: R-HSA-392517
Cellular Localisation Nucleus
Cytoplasm
Perinuclear Region
Endomembrane System
Peripheral Membrane Protein
Mostly Localized In The Perinuclear Membraneous Region
Alternative Antibody Names Anti-Signal-Induced Proliferation-Associated Protein 1 antibody
Anti-Sipa-1 antibody
Anti-Gtpase-Activating Protein Spa-1 antibody
Anti-P130 Spa-1 antibody
Anti-SIPA1 antibody
Anti-SPA1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance