Anti-SOX13 antibody (1-180) (STJ118204)

Name: Anti-SOX13 antibody (1-180) (STJ118204)
SKU: STJ118204
Availability: InStock

⇓ Datasheet ⇓ SDS Citations

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ118204

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Short Description	Rabbit polyclonal SOX13 (1-180) antibody for use in WB and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:1000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	SOX13
Gene ID	9580
Uniprot ID	SOX13_HUMAN
Immunogen Region	1-180
Immunogen Sequence	MSMRSPISAQLALDGVGTMV NCTIKSEEKKEPCHEAPQGS ATAAEPQPGDPARASQDSAD PQAPAQGNFRGSWDCSSPEG NGSPEPKRPGVSEAASGSQE KLDFNRNLKEVVPAIEKLLS SDWKERFLGRNSMEAKDVKG TQESLAEKELQLLVMIHQLS TLRDQLLTAHSEQKNMAAML
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human SOX13 (NP_005677.2).

Tissue Specificity	Expressed in exocrine cells and islets of Langerhans in the pancreas (at protein level). Expressed in the pancreas, placenta, kidney, brain, heart, lung, and liver. Expressed in adipose tissue, cervix, colon, esophagus, ovary, prostate, small intestine, spleen, testicle, thymus and thyroid.
Function	Transcription factor that binds to DNA at the consensus sequence 5'-AACAAT-3'. Binds to the proximal promoter region of the myelin protein MPZ gene, and may thereby be involved in the differentiation of oligodendroglia in the developing spinal tube. Binds to the gene promoter of MBP and acts as a transcriptional repressor. Binds to and modifies the activity of TCF7/TCF1, thereby inhibiting transcription and modulates normal gamma-delta T-cell development and differentiation of IL17A expressing gamma-delta T-cells. Regulates expression of BLK in the differentiation of IL17A expressing gamma-delta T-cells. Promotes brown adipocyte differentiation. Inhibitor of WNT signaling.
Protein Name	Transcription Factor Sox-13 Islet Cell Antigen 12 Sry Sex Determining Region Y-Box 13 Type 1 Diabetes Autoantigen Ica12
Database Links	Reactome: R-HSA-3769402
Cellular Localisation	Nucleus Cytoplasm
Alternative Antibody Names	Anti-Transcription Factor Sox-13 antibody Anti-Islet Cell Antigen 12 antibody Anti-Sry antibody Anti-Sex Determining Region Y-Box 13 antibody Anti-Type 1 Diabetes Autoantigen Ica12 antibody Anti-SOX13 antibody

Information sourced from Uniprot.org