Anti-SOX11 antibody (1-100) (STJ119929)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SOX11 (1-100) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SOX11 |
| Gene ID | 6664 |
| Uniprot ID | SOX11_HUMAN |
| Immunogen Region | 1-100 |
| Immunogen Sequence | MVQQAESLEAESNLPREALD TEEGEFMACSPVALDESDPD WCKTASGHIKRPMNAFMVWS KIERRKIMEQSPDMHNAEIS KRLGKRWKMLKDSEKIPFIR |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SOX11 (NP_003099.1). |
Additional Info
| Tissue Specificity | Expressed primarily in the brain and heart, with low expression in the kidney, pancreas and muscle. |
| Function | Transcription factor that acts as a transcriptional activator. Binds cooperatively with POU3F2/BRN2 or POU3F1/OCT6 to gene promoters, which enhances transcriptional activation. Acts as a transcriptional activator of TEAD2 by binding to its gene promoter and first intron. Plays a redundant role with SOX4 and SOX12 in cell survival of developing tissues such as the neural tube, branchial arches and somites, thereby contributing to organogenesis. |
| Protein Name | Transcription Factor Sox-11 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Factor Sox-11 antibodyAnti-SOX11 antibody |
Information sourced from Uniprot.org