SOS1 antibody western blot HeLa cells STJA0036398

Anti-SOS1 antibody [R05-8C9] (STJA0036398)

Name: Anti-SOS1 antibody [R05-8C9] (STJA0036398)
SKU: STJA0036398
Availability: InStock

⇓ Datasheet ⇓ SDS Citations

SPECIFICATIONS

ClonalityMonoclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

ImmunogenA synthesized peptide derived from human SOS1

STJA0036398

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General Information

Short Description	Rabbit monoclonal anti-SOS1 for use in WB, IHC-P, ICC and IF in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC-P/ICC/IF
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Clonality	Monoclonal
Clone ID	R05-8C9
Isotype	IgG
Conjugation	Unconjugated
Purification	Affinity Chromatography
Dilution Range	WB 1:500-1:1000 IHC 1:50-1:100 IF 1:50-1:200
Formulation	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Instruction	Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.

Target Information

Gene Symbol	SOS1
Gene ID	6654
Uniprot ID	SOS1_HUMAN
Immunogen	A synthesized peptide derived from human SOS1

Additional Info

Tissue Specificity	Expressed in gingival tissues.
Post Translational Modifications	Phosphorylation at Ser-1134 and Ser-1161 by RPS6KA3 create YWHAB and YWHAE binding sites and which contribute to the negative regulation of EGF-induced MAPK1/3 phosphorylation.
Function	Promotes the exchange of Ras-bound GDP by GTP. Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3/ERK1 in response to EGF. Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor (GEF) activity.
Protein Name	Son Of Sevenless Homolog 1 Sos-1
Database Links	Reactome: R-HSA-112412 Reactome: R-HSA-1236382 Reactome: R-HSA-1250196 Reactome: R-HSA-1250347 Reactome: R-HSA-1433557 Reactome: R-HSA-1433559 Reactome: R-HSA-167044 Reactome: R-HSA-179812 Reactome: R-HSA-180336 Reactome: R-HSA-186763 Reactome: R-HSA-193648 Reactome: R-HSA-1963640 Reactome: R-HSA-210993 Reactome: R-HSA-2179392 Reactome: R-HSA-2424491 Reactome: R-HSA-2428933 Reactome: R-HSA-2730905 Reactome: R-HSA-2871796 Reactome: R-HSA-2871809 Reactome: R-HSA-354194 Reactome: R-HSA-375165 Reactome: R-HSA-416482 Reactome: R-HSA-428540 Reactome: R-HSA-5637810 Reactome: R-HSA-5654688 Reactome: R-HSA-5654693 Reactome: R-HSA-5654699 Reactome: R-HSA-5654700 Reactome: R-HSA-5654704 Reactome: R-HSA-5654706 Reactome: R-HSA-5654712 Reactome: R-HSA-5654719 Reactome: R-HSA-5655253 Reactome: R-HSA-5655291 Reactome: R-HSA-5655302 Reactome: R-HSA-5655332 Reactome: R-HSA-5673001 Reactome: R-HSA-74749 Reactome: R-HSA-74751 Reactome: R-HSA-8851805 Reactome: R-HSA-8853659 Reactome: R-HSA-8983432 Reactome: R-HSA-9013149 Reactome: R-HSA-9026519 Reactome: R-HSA-9027284 Reactome: R-HSA-9028731 Reactome: R-HSA-9034864 Reactome: R-HSA-912526 Reactome: R-HSA-9607240 Reactome: R-HSA-9634285 Reactome: R-HSA-9664565 Reactome: R-HSA-9665348 Reactome: R-HSA-9665686 Reactome: R-HSA-9670439 Reactome: R-HSA-9673767 Reactome: R-HSA-9673770 Reactome: R-HSA-9679191 Reactome: R-HSA-9680350 Reactome: R-HSA-9703465 Reactome: R-HSA-9703648 Reactome: R-HSA-983695 Reactome: R-HSA-9842663
Cellular Localisation
Alternative Antibody Names	Anti-Son Of Sevenless Homolog 1 antibody Anti-Sos-1 antibody Anti-SOS1 antibody

Information sourced from Uniprot.org

Citations

View product citations for antibody STJA0036398 on CiteAb