Anti-SORCS3 antibody (C-Term) (STJ13102057)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from the c-terminal region of human SORCS3 conjugated to an immunogenic carrier protein was used as the antigen. The antigen shares 95% identity with mouse sequence.
General Information
| Short Description | Rabbit polyclonal anti-SORCS3 (C-Term) for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | SORCS3 |
| Gene ID | 22986 |
| Uniprot ID | SORC3_HUMAN |
| Immunogen | A synthetic peptide from the c-terminal region of human SORCS3 conjugated to an immunogenic carrier protein was used as the antigen. The antigen shares 95% identity with mouse sequence. |
| Immunogen Region | C-Term |
| Specificity | Specific for SORCS3. |
Additional Info
| Function | Plays an important role in modulating synaptic transmission and plasticity in the hippocampus, probably by affecting the trafficking and localization ofAMPA-type glutamate receptors in the postsynaptic density. |
| Protein Name | Vps10 Domain-Containing Receptor Sorcs3 |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinSynaptic Cell MembranePostsynaptic Density |
| Alternative Antibody Names | Anti-Vps10 Domain-Containing Receptor Sorcs3 antibodyAnti-SORCS3 antibodyAnti-KIAA1059 antibody |
Information sourced from Uniprot.org