Anti-SOAT1 antibody (1-130) (STJ28233)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SOAT1 (1-130) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SOAT1 |
| Gene ID | 6646 |
| Uniprot ID | SOAT1_HUMAN |
| Immunogen Region | 1-130 |
| Immunogen Sequence | MVGEEKMSLRNRLSKSRENP EEDEDQRNPAKESLETPSNG RIDIKQLIAKKIKLTAEAEE LKPFFMKEVGSHFDDFVTNL IEKSASLDNGGCALTTFSVL EGEKNNHRAKDLRAPPEQGK IFIARRSLLD |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human SOAT1 (NP_003092.4). |
Additional Info
| Function | Catalyzes the formation of fatty acid-cholesterol esters, which are less soluble in membranes than cholesterol. Plays a role in lipoprotein assembly and dietary cholesterol absorption. Preferentially utilizes oleoyl-CoA ((9Z)-octadecenoyl-CoA) as a substrate: shows a higher activity towards an acyl-CoA substrate with a double bond at the delta-9 position (9Z) than towards saturated acyl-CoA or an unsaturated acyl-CoA with a double bond at the delta-7 (7Z) or delta-11 (11Z) positions. |
| Protein Name | Sterol O-Acyltransferase 1Acyl-Coenzyme A -Cholesterol Acyltransferase 1Acat-1Cholesterol Acyltransferase 1 |
| Database Links | Reactome: R-HSA-8964038 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Sterol O-Acyltransferase 1 antibodyAnti-Acyl-Coenzyme A -Cholesterol Acyltransferase 1 antibodyAnti-Acat-1 antibodyAnti-Cholesterol Acyltransferase 1 antibodyAnti-SOAT1 antibodyAnti-ACACT antibodyAnti-ACACT1 antibodyAnti-ACAT antibodyAnti-ACAT1 antibodyAnti-SOAT antibodyAnti-STAT antibody |
Information sourced from Uniprot.org