| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Sorting nexin-33 (55-105 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SNX33 |
| Gene ID: |
257364 |
| Uniprot ID: |
SNX33_HUMAN |
| Immunogen Region: |
55-105 aa |
| Specificity: |
This antibody detects endogenous levels of SNX33 at Human/Mouse |
| Immunogen: |
Synthesized peptide derived from the human SNX33 at the amino acid range 55-105 |
| Post Translational Modifications | Phosphorylated. |
| Function | Plays a role in the reorganization of the cytoskeleton, endocytosis and cellular vesicle trafficking via its interactions with membranes, WASL, DNM1 and DNM2. Acts both during interphase and at the end of mitotic cell divisions. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Modulates endocytosis of cell-surface proteins, such as APP and PRNP.this then modulates the secretion of APP and PRNP peptides. Promotes membrane tubulation (in vitro). May promote the formation of macropinosomes. |
| Protein Name | Sorting Nexin-33Sh3 And Px Domain-Containing Protein 3 |
| Cellular Localisation | CytoplasmCytosolMembranePeripheral Membrane ProteinCytoplasmic SideCytoplasmic Vesicle MembranePrimarily CytosolicBut A Minor Proportion Is Membrane-BoundNot Associated With Membranes |
| Alternative Antibody Names | Anti-Sorting Nexin-33 antibodyAnti-Sh3 And Px Domain-Containing Protein 3 antibodyAnti-SNX33 antibodyAnti-SH3PX3 antibodyAnti-SH3PXD3C antibodyAnti-SNX30 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
