| Host: | Goat |
| Applications: | Pep-ELISA/WB/IHC/ICC |
| Reactivity: | Human/Mouse/Rat/Dog/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-SNX1 (Internal) is suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Approx 75kDa band observed in lysates of cell lines HeLa and U2OS (calculated MW of 59.1kDa according to NP_003090.2). This molecular weight is routinely observed by other sources. Rec |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | SNX1 |
| Gene ID: | 6642 |
| Uniprot ID: | SNX1_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_003090.2; NP_690039.1 |
| Specificity: | This antibody is expected to recognize isoform a and c (NP_003090.2; NP_690039.1. |
| Immunogen Sequence: | TNSSKPQPTYEELE |
| Protein Name | Sorting Nexin-1 |
| Cellular Localisation | Endosome MembranePeripheral Membrane ProteinCytoplasmic SideGolgi ApparatusTrans-Golgi Network MembraneEarly Endosome MembraneCell ProjectionLamellipodiumEnriched On Tubular Elements Of The Early Endosome MembraneBinds Preferentially To Highly Curved Membranes Enriched In Phosphatidylinositol 3-Phosphate (Ptdins(3p)) Or Phosphatidylinositol 35-Bisphosphate (Ptdins(35)P2)Colocalized With Sort1 To Tubular Endosomal Membrane Structures Called Endosome-To-Tgn Transport Carriers (Etcs) Which Are Budding From Early Endosome Vacuoles Just Before Maturing Into Late Endosome VacuolesColocalizes With Dnajc13 And Shiginella Dysenteria Toxin Stxb On Early EndosomesColocalized With F-Actin At The Leading Edge Of Lamellipodia In A Kalrn-Dependent Manner |
| Alternative Antibody Names | Anti-Sorting Nexin-1 antibodyAnti-SNX1 antibody |
Information sourced from Uniprot.org
