Anti-SND1 antibody [SRM14847] (STJ11109577)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
General Information
| Short Description | Rabbit monoclonal SND1 antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM14847 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity purification |
| Dilution Range | WB, 1:10000-1:40000IHC-P, 1:5000-1:20000IF/ICC, 1:200-1:800ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SND1 |
| Gene ID | 27044 |
| Uniprot ID | SND1_HUMAN |
| Immunogen | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
Additional Info
| Tissue Specificity | Ubiquitously expressed. |
| Post Translational Modifications | Phosphorylated by PIM1 in vitro. |
| Function | Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. As part of its function in miRNA decay, regulates mRNAs involved in G1-to-S phase transition. Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1 regulation of MYB activity. Functions as a transcriptional coactivator for STAT5. (Microbial infection) Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2). (Microbial infection) Promotes SARS-CoV-2 RNA synthesis by binding to negative-sense RNA and the viral protein nsp9. |
| Protein Name | Staphylococcal Nuclease Domain-Containing Protein 1100 Kda CoactivatorEbna2 Coactivator P100Tudor Domain-Containing Protein 11P100 Co-Activator |
| Database Links | Reactome: R-HSA-6802952 |
| Cellular Localisation | CytoplasmNucleusMelanosomeIn Il-4 Stimulated Cells Colocalizes With Stat6 In The NucleusIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
| Alternative Antibody Names | Anti-Staphylococcal Nuclease Domain-Containing Protein 1 antibodyAnti-100 Kda Coactivator antibodyAnti-Ebna2 Coactivator P100 antibodyAnti-Tudor Domain-Containing Protein 11 antibodyAnti-P100 Co-Activator antibodyAnti-SND1 antibodyAnti-TDRD11 antibody |
Information sourced from Uniprot.org