Anti-SND1 antibody (26-285) (STJ28147)

Name: Anti-SND1 antibody (26-285) (STJ28147)
SKU: STJ28147
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ28147

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Short Description	Rabbit polyclonal SND1 (26-285) antibody for use in WB, IHC-P, IF, ICC, IP and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC-P/IF/ICC/IP/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 IHC-P:1:50-1:200 IF/ICC:1:50-1:200 IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cells ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specif
Formulation	PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	SND1
Gene ID	27044
Uniprot ID	SND1_HUMAN
Immunogen Region	26-285
Immunogen Sequence	MVLSGCAIIVRGQPRGGPPP ERQINLSNIRAGNLARRAAA TQPDAKDTPDEPWAFPAREF LRKKLIGKEVCFTIENKTPQ GREYGMIYLGKDTNGENIAE SLVAEGLATRREGMRANNPE QNRLSECEEQAKAAKKGMWS EGNGSHTIRDLKYTIENPRH FVDSHHQKPVNAIIEHVRDG SVVRALLLPDYYLVTVMLSG IKCPTFRREADGSETPEPFA AEAKFFTESRLLQRDVQII
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 26-285 of human SND1 (NP_055205.2).

Tissue Specificity	Ubiquitously expressed.
Post Translational Modifications	Phosphorylated by PIM1 in vitro.
Function	Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. As part of its function in miRNA decay, regulates mRNAs involved in G1-to-S phase transition. Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1 regulation of MYB activity. Functions as a transcriptional coactivator for STAT5. (Microbial infection) Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2). (Microbial infection) Promotes SARS-CoV-2 RNA synthesis by binding to negative-sense RNA and the viral protein nsp9.
Protein Name	Staphylococcal Nuclease Domain-Containing Protein 1 100 Kda Coactivator Ebna2 Coactivator P100 Tudor Domain-Containing Protein 11 P100 Co-Activator
Database Links	Reactome: R-HSA-6802952
Cellular Localisation	Cytoplasm Nucleus Melanosome In Il-4 Stimulated Cells Colocalizes With Stat6 In The Nucleus Identified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv
Alternative Antibody Names	Anti-Staphylococcal Nuclease Domain-Containing Protein 1 antibody Anti-100 Kda Coactivator antibody Anti-Ebna2 Coactivator P100 antibody Anti-Tudor Domain-Containing Protein 11 antibody Anti-P100 Co-Activator antibody Anti-SND1 antibody Anti-TDRD11 antibody

Information sourced from Uniprot.org