Anti-SMYD1 antibody (1-350) (STJ26205)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SMYD1 (1-350) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:2000IHC-P:1:20-1:200IF/ICC:1:20-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SMYD1 |
| Gene ID | 150572 |
| Uniprot ID | SMYD1_HUMAN |
| Immunogen Region | 1-350 |
| Immunogen Sequence | MTIGRMENVEVFTAEGKGRG LKATKEFWAADIIFAERAYS AVVFDSLVNFVCHTCFKRQE KLHRCGQCKFAHYCDRTCQK DAWLNHKNECSAIKRYGKVP NENIRLAARIMWRVEREGTG LTEGCLVSVDDLQNHVEHFG EEEQKDLRVDVDTFLQYWPP QSQQFSMQYISHIFGVINCN GFTLSDQRGLQAVGVGIFPN LGLVNHDCWPNCTVIFNNGN HEAVKSMFHTQMRIELRAL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human SMYD1 (NP_938015.1). |
Additional Info
| Tissue Specificity | Expression seems mostly restricted to heart and skeletal muscle. |
| Function | Methylates histone H3 at 'Lys-4' (H3K4me), seems able to perform both mono-, di-, and trimethylation. Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis. |
| Protein Name | Histone-Lysine N-Methyltransferase Smyd1Set And Mynd Domain-Containing Protein 1 |
| Database Links | Reactome: R-HSA-9733709 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Histone-Lysine N-Methyltransferase Smyd1 antibodyAnti-Set And Mynd Domain-Containing Protein 1 antibodyAnti-SMYD1 antibody |
Information sourced from Uniprot.org