Anti-SMPD2 antibody (150-250) (STJ25629)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SMPD2 (150-250) antibody for use in WB and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SMPD2 |
| Gene ID | 6610 |
| Uniprot ID | NSMA_HUMAN |
| Immunogen Region | 150-250 |
| Immunogen Sequence | AHRVAQAWELAQFIHHTSKK ADVVLLCGDLNMHPEDLGCC LLKEWTGLHDAYLETRDFKG SEEGNTMVPKNCYVSQQELK PFPFGVRIDYVLYKAVSGFY I |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 150-250 of human SMPD2 (NP_003071.2). |
Additional Info
| Function | Catalyzes, at least in vitro, the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Also hydrolyzes 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine (lyso-platelet-activating factor) in vivo. Also acts on 1-acyl-2-lyso-sn-glycero-3-phosphocholine (lyso-PC) and sphingosylphosphocholine. |
| Protein Name | Sphingomyelin Phosphodiesterase 2Lyso-Platelet-Activating Factor-Phospholipase CLyso-Paf-PlcNeutral SphingomyelinaseN-SmaseNsmaseNsmase1 |
| Database Links | Reactome: R-HSA-193681Reactome: R-HSA-5626978Reactome: R-HSA-9840310 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Sphingomyelin Phosphodiesterase 2 antibodyAnti-Lyso-Platelet-Activating Factor-Phospholipase C antibodyAnti-Lyso-Paf-Plc antibodyAnti-Neutral Sphingomyelinase antibodyAnti-N-Smase antibodyAnti-Nsmase antibodyAnti-Nsmase1 antibodyAnti-SMPD2 antibody |
Information sourced from Uniprot.org