Anti-SMOX antibody (212-262 aa) (STJ194304)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human SMOX at the amino acid range 212-262
General Information
| Short Description | Rabbit polyclonal anti-Spermine oxidase (212-262 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SMOX |
| Gene ID | 54498 |
| Uniprot ID | SMOX_HUMAN |
| Immunogen | Synthesized peptide derived from the human SMOX at the amino acid range 212-262 |
| Immunogen Region | 212-262 aa |
| Specificity | This antibody detects endogenous levels of SMOX at Human/Mouse |
Additional Info
| Function | Flavoenzyme which catalyzes the oxidation of spermine to spermidine. Can also use N(1)-acetylspermine and spermidine as substrates, with different affinity depending on the isoform (isozyme) and on the experimental conditions. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. May contribute to beta-alanine production via aldehyde dehydrogenase conversion of 3-amino-propanal. |
| Protein Name | Spermine OxidasePolyamine Oxidase 1Pao-1Paoh1 |
| Database Links | Reactome: R-HSA-141334 Q9NWM0-3Reactome: R-HSA-351200 Q9NWM0-3 |
| Cellular Localisation | Isoform 1: CytoplasmNucleusIsoform 4: CytoplasmIsoform 6: Cytoplasm |
| Alternative Antibody Names | Anti-Spermine Oxidase antibodyAnti-Polyamine Oxidase 1 antibodyAnti-Pao-1 antibodyAnti-Paoh1 antibodyAnti-SMOX antibodyAnti-C20orf16 antibodyAnti-SMO antibodyAnti-UNQ3039 antibodyAnti-PRO9854 antibody |
Information sourced from Uniprot.org