Anti-SMNDC1 antibody (1-238) (STJ25626)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SMNDC1 (1-238) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SMNDC1 |
| Gene ID | 10285 |
| Uniprot ID | SPF30_HUMAN |
| Immunogen Region | 1-238 |
| Immunogen Sequence | MSEDLAKQLASYKAQLQQVE AALSGNGENEDLLKLKKDLQ EVIELTKDLLSTQPSETLAS SDSFASTQPTHSWKVGDKCM AVWSEDGQCYEAEIEEIDEE NGTAAITFAGYGNAEVTPLL NLKPVEEGRKAKEDSGNKPM SKKEMIAQQREYKKKKALKK AQRIKELEQEREDQKVKWQQ FNNRAYSKNKKGQVKRSIFA SPESVTGKVGVGTCGIADKP MTQYQDTSKYNVRHLMPQ |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-238 of human SMNDC1 (NP_005862.1). |
Additional Info
| Tissue Specificity | Detected at intermediate levels in skeletal muscle, and at low levels in heart and pancreas. |
| Function | Involved in spliceosome assembly. |
| Protein Name | Survival Of Motor Neuron-Related-Splicing Factor 3030 Kda Splicing Factor SmnrpSmn-Related ProteinSurvival Motor Neuron Domain-Containing Protein 1 |
| Database Links | Reactome: R-HSA-72163 |
| Cellular Localisation | Nucleus SpeckleNucleusCajal BodyDetected In Nuclear Speckles Containing Snrnp And In Cajal (Coiled) Bodies |
| Alternative Antibody Names | Anti-Survival Of Motor Neuron-Related-Splicing Factor 30 antibodyAnti-30 Kda Splicing Factor Smnrp antibodyAnti-Smn-Related Protein antibodyAnti-Survival Motor Neuron Domain-Containing Protein 1 antibodyAnti-SMNDC1 antibodyAnti-SMNR antibodyAnti-SPF30 antibody |
Information sourced from Uniprot.org