Anti-SMC1B antibody (110-190 aa) (STJ192510)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 110-190
STJ192510
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General Information

Short DescriptionRabbit polyclonal anti-Structural maintenance of chromosomes protein 1B (110-190 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/ELISA
HostRabbit
ReactivityHuman/Rat/Mouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeWB 1:500-2000
ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolSMC1B
Gene ID27127
Uniprot IDSMC1B_HUMAN
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 110-190
Immunogen Region110-190 aa
SpecificitySMC1B Polyclonal Antibody detects endogenous levels of protein.

Additional Info

Protein Name Structural Maintenance Of Chromosomes Protein 1b
Smc Protein 1b
Smc-1-Beta
Smc-1b
Database Links Reactome: R-HSA-1221632
Cellular Localisation Nucleus
Chromosome
Centromere
Associates With Chromatin
In Prophase I Stage Of Meiosis
Localizes Along The Ae Of Synaptonemal Complexes
In Late-Pachytene-Diplotene
The Bulk Of Protein Dissociates From The Chromosome Arms Probably Because Of Phosphorylation By Plk
Except At Centromeres
Where Cohesin Complexes Remain
Remains Chromatin Associated At The Centromeres Up To Metaphase Ii
At Anaphase Ii
Dissociates From Centromeres
Allowing Chromosomes Segregation
Alternative Antibody Names Anti-Structural Maintenance Of Chromosomes Protein 1b antibody
Anti-Smc Protein 1b antibody
Anti-Smc-1-Beta antibody
Anti-Smc-1b antibody
Anti-SMC1B antibody
Anti-SMC1L2 antibody

Information sourced from Uniprot.org

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