Anti-SLMAP antibody (540-790) (STJ11102829)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SLMAP (540-790) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLMAP |
| Gene ID | 7871 |
| Uniprot ID | SLMAP_HUMAN |
| Immunogen Region | 540-790 |
| Immunogen Sequence | IDTENLREEKDSEITSTRDE LLSARDEILLLHQAAAKVAS ERDTDIASLQEELKKVRAEL ERWRKAASEYEKEITSLQNS FQLRCQQCEDQQREEATRLQ GELEKLRKEWNALETECHSL KRENVLLSSELQRQEKELHN SQKQSLELTSDLSILQMSRK ELENQVGSLKEQHLRDSADL KTLLSKAENQAKDVQKEYEK TQTVLSELKLKFEMTEQEKQ SITDELKQCKNNLKLLREK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 540-790 of human SLMAP (NP_009090.2). |
Additional Info
| Function | Associates with the striatin-interacting phosphatase and kinase (STRIPAK) core complex, forming the extended (SIKE1:SLMAP)STRIPAK complex. The (SIKE1:SLMAP)STRIPAK complex dephosphorylates STK3 leading to the inhibition of Hippo signaling and the control of cell growth. May play a role during myoblast fusion. |
| Protein Name | Sarcolemmal Membrane-Associated ProteinSarcolemmal-Associated Protein |
| Database Links | |
| Cellular Localisation | Cell MembraneSarcolemmaSingle-Pass Type Iv Membrane ProteinCytoplasmMyofibrilSarcomereM LineZ LineCytoskeletonMicrotubule Organizing CenterCentrosomeMembrane-AssociatedDistributed In The Transverse Tubules And Near The Junctional Sarcoplasmic ReticulumDetected Along The Z- And M-Lines In CardiomyocytesIsoform 1: Endoplasmic Reticulum MembraneMitochondrion MembraneIsoform 2: Endoplasmic Reticulum MembraneIsoform 3: Endoplasmic Reticulum MembraneIsoform 4: Endoplasmic Reticulum MembraneIsoform 5: Endoplasmic Reticulum MembraneDo Not Localize At The Mitochondrial Membrane |
| Alternative Antibody Names | Anti-Sarcolemmal Membrane-Associated Protein antibodyAnti-Sarcolemmal-Associated Protein antibodyAnti-SLMAP antibodyAnti-KIAA1601 antibodyAnti-SLAP antibodyAnti-UNQ1847 antibodyAnti-PRO3577 antibody |
Information sourced from Uniprot.org