Anti-SLITRK1 antibody (410-460 aa) (STJ13102257)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from aa region 410-460 of human SLITRK1 conjugated to an immunogenic carrier protein was used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-SLITRK1 (410-460 aa) for use in IHC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB (confirmed by recombinant protein). A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | SLITRK1 |
| Gene ID | 114798 |
| Uniprot ID | SLIK1_HUMAN |
| Immunogen | A synthetic peptide from aa region 410-460 of human SLITRK1 conjugated to an immunogenic carrier protein was used as the antigen. |
| Immunogen Region | 410-460 aa |
| Specificity | Specific for SLITRK1. |
Additional Info
| Post Translational Modifications | Undergoes proteolytic cleavage that results in shedding of the ectodomain and cleavage of the C-terminal cytoplasmic tail. Glycosylated. Phosphorylation at Ser-695 is necessary for proper function in promoting neurite outgrowth. |
| Function | It is involved in synaptogenesis and promotes excitatory synapse differentiation. Enhances neuronal dendrite outgrowth. |
| Protein Name | Slit And Ntrk-Like Protein 1Leucine-Rich Repeat-Containing Protein 12 |
| Database Links | Reactome: R-HSA-388844 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinSecretedSynapse |
| Alternative Antibody Names | Anti-Slit And Ntrk-Like Protein 1 antibodyAnti-Leucine-Rich Repeat-Containing Protein 12 antibodyAnti-SLITRK1 antibodyAnti-KIAA1910 antibodyAnti-LRRC12 antibodyAnti-UNQ233 antibodyAnti-PRO266 antibody |
Information sourced from Uniprot.org