Anti-SLC9A3 antibody (490-570 aa) (STJ190164)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 490-570
General Information
| Short Description | Rabbit polyclonal anti-Sodium/hydrogen exchanger 3/H+ exchanger 3 (490-570 aa) for use in WB and ELISA in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC9A3 |
| Gene ID | 6550 |
| Uniprot ID | SL9A3_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 490-570 |
| Immunogen Region | 490-570 aa |
| Specificity | SL9A3 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Plasma membrane Na(+)/H(+) antiporter. Exchanges intracellular H(+) ions for extracellular Na(+) in 1:1 stoichiometry, playing a key role in salt and fluid absorption and pH homeostasis. Major apical Na(+)/H(+) exchanger in kidney and intestine playing an important role in renal and intestine Na(+) absorption and blood pressure regulation. |
| Protein Name | Sodium/Hydrogen Exchanger 3Na(+/H(+ Exchanger 3Nhe-3Solute Carrier Family 9 Member 3 |
| Database Links | Reactome: R-HSA-425986 |
| Cellular Localisation | Apical Cell MembraneMulti-Pass Membrane ProteinCell MembraneRecycling Endosome MembraneEarly Endosome MembraneIn Intestinal Epithelial CellsLocalizes To The Ileal Brush BorderPhosphorylation At Ser-663 By Sgk1 Is Associated With Increased Abundance At The Cell MembraneAngiotensin-2 Enhances Apical Expression |
| Alternative Antibody Names | Anti-Sodium/Hydrogen Exchanger 3 antibodyAnti-Na(+/H(+ Exchanger 3 antibodyAnti-Nhe-3 antibodyAnti-Solute Carrier Family 9 Member 3 antibodyAnti-SLC9A3 antibodyAnti-NHE3 antibody |
Information sourced from Uniprot.org