Anti-SLC7A7 antibody (N-Term) (STJ13101384)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from n-terminal region of human Monocyte amino acid permease 2 (MOP-2, SLC7A7) conjugated to blue carrier protein was used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-SLC7A7 (N-Term) for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB (confirmed by recombinant protein). A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20ยฐC for long term storage and refrigerated at 2-8ยฐC for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | SLC7A7 |
| Gene ID | 9056 |
| Uniprot ID | YLAT1_HUMAN |
| Immunogen | A synthetic peptide from n-terminal region of human Monocyte amino acid permease 2 (MOP-2, SLC7A7) conjugated to blue carrier protein was used as the antigen. |
| Immunogen Region | N-Term |
| Specificity | Specific for MOP-2. |
Additional Info
| Function | Heterodimer with SLC3A2, that functions as an antiporter which operates as an efflux route by exporting cationic amino acids from inside the cells in exchange with neutral amino acids plus sodium ions and may participate in nitric oxide synthesis via the transport of L-arginine. Also mediates arginine transport in non-polarized cells, such as monocytes, and is essential for the correct function of these cells. The transport mechanism is electroneutral and operates with a stoichiometry of 1:1. In vitro, Na(+) and Li(+), but also H(+), are cotransported with the neutral amino acids. |
| Protein Name | Y+L Amino Acid Transporter 1Monocyte Amino Acid Permease 2Mop-2Solute Carrier Family 7 Member 7Y(+L-Type Amino Acid Transporter 1Y+Lat1Y+Lat-1 |
| Database Links | Reactome: R-HSA-210991Reactome: R-HSA-352230Reactome: R-HSA-5660862 |
| Cellular Localisation | Basolateral Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Y+L Amino Acid Transporter 1 antibodyAnti-Monocyte Amino Acid Permease 2 antibodyAnti-Mop-2 antibodyAnti-Solute Carrier Family 7 Member 7 antibodyAnti-Y(+L-Type Amino Acid Transporter 1 antibodyAnti-Y+Lat1 antibodyAnti-Y+Lat-1 antibodyAnti-SLC7A7 antibody |
Information sourced from Uniprot.org