Anti-SLC6A6 antibody (250-320) (STJ116983)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SLC6A6 (250-320) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC6A6 |
| Gene ID | 6533 |
| Uniprot ID | SC6A6_HUMAN |
| Immunogen Region | 250-320 |
| Immunogen Sequence | LFQSFQKELPWAHCNHSWNT PHCMEDTMRKNKSVWITISS TNFTSPVIEFWERNVLSLSP GIDHPGSLKWD |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 250-320 of human SLC6A6 (NP_001127839.2). |
Additional Info
| Tissue Specificity | Expressed abundantly in placenta and skeletal muscle, at intermediate levels in heart, brain, lung, kidney and pancreas and at low levels in liver. |
| Post Translational Modifications | Taurine transport activity is down-regulated upon Ser-322 phosphorylation. |
| Function | Mediates sodium- and chloride-dependent transport of taurine. Mediates transport of beta-alanine. Can also mediate transport of hypotaurine and gamma-aminobutyric acid (GABA). Sodium-dependent taurine and beta-alanine transporter. Chloride ions are necessary for optimal uptake. |
| Protein Name | Sodium- And Chloride-Dependent Taurine TransporterSolute Carrier Family 6 Member 6 |
| Database Links | Reactome: R-HSA-352230Reactome: R-HSA-442660 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Sodium- And Chloride-Dependent Taurine Transporter antibodyAnti-Solute Carrier Family 6 Member 6 antibodyAnti-SLC6A6 antibody |
Information sourced from Uniprot.org