Anti-SLC6A5 antibody (250-350) [S4119RM] (STJ11104119)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Sodium-And Chloride-Dependent Glycine Transporter 2 (250-350) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S4119RM |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC6A5 |
| Gene ID | 9152 |
| Uniprot ID | SC6A5_HUMAN |
| Immunogen Region | 250-350 |
| Immunogen Sequence | SLGQFASQGPVSVWKAIPAL QGCGIAMLIISVLIAIYYNV IICYTLFYLFASFVSVLPWG SCNNPWNTPECKDKTKLLLD SCVISDHPKIQIKNSTFCMT A |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human Glyt2 (Q9Y345). |
Additional Info
| Tissue Specificity | Expressed in medulla, and to a lesser extent in spinal cord and cerebellum. |
| Post Translational Modifications | N-glycosylated. |
| Function | Sodium- and chloride-dependent glycine transporter. Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals. May be responsible for the termination of neurotransmission at strychnine-sensitive glycinergic synapses. Isoform 2: Lacks sodium- and chloride-dependent glycine transporter activity. Isoform 3: Lacks sodium- and chloride-dependent glycine transporter activity. |
| Protein Name | Sodium- And Chloride-Dependent Glycine Transporter 2Glyt-2Glyt2Solute Carrier Family 6 Member 5 |
| Database Links | Reactome: R-HSA-442660Reactome: R-HSA-5619089 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Sodium- And Chloride-Dependent Glycine Transporter 2 antibodyAnti-Glyt-2 antibodyAnti-Glyt2 antibodyAnti-Solute Carrier Family 6 Member 5 antibodyAnti-SLC6A5 antibodyAnti-GLYT2 antibodyAnti-NET1 antibody |
Information sourced from Uniprot.org