Name: Anti-SLC6A3 antibody (C-Term) (STJA0003616)
SKU: STJA0003616-100
Price: 488.5 GBP
Availability: InStock

Anti-SLC6A3 antibody (C-Term) (STJA0003616)

SKU:

STJA0003616-100

£488.50

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Short Description :	Rabbit polyclonal anti-Dopamine Transporter (C-Term) for use in WB and IHC in Human, Mouse, Non-Human Primates and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:	WB/IHC
Host:	Rabbit
Reactivity:	Human/Mouse/Non-Human Primates/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality :	Polyclonal
Isotype:	IgG
Conjugation:	Unconjugated
Purification:	This antibody was antigen affinity purified from pooled serum.
Dilution Range:	WB 1:1000 IHC 1:100-1:1000
Formulation:	100 µl in 10 mM HEPES (pH 7.5) , 150 mM NaCl, 100 µg per ml BSA and 50% Glycerol.
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	SLC6A3
Gene ID:	6531
Uniprot ID:	SC6A3_HUMAN
Immunogen:	Synthetic peptide corresponding to amino acid residues from the intracellular C-terminal region conjugated to KLH.
Immunogen Region:	C-Term

Tissue Specificity	Highly expressed in substantia nigra. Expressed in axonal varicosities in dopaminergic nerve terminals (at protein level). Expressed in the striatum (at protein level).
Function	Mediates sodium- and chloride-dependent transport of dopamine. Also mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline). Regulator of light-dependent retinal hyaloid vessel regression, downstream of OPN5 signaling.
Protein Name	Sodium-Dependent Dopamine Transporter Da Transporter Dat Solute Carrier Family 6 Member 3
Database Links	Reactome: R-HSA-379401 Reactome: R-HSA-442660 Reactome: R-HSA-5619081 Reactome: R-HSA-5660724
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein Cell Projection Neuron Projection Axon Localizes To Neurite Tips In Neuronal Cells Colocalizes With Septin4 At Axon Terminals Especially At The Varicosities
Alternative Antibody Names	Anti-Sodium-Dependent Dopamine Transporter antibody Anti-Da Transporter antibody Anti-Dat antibody Anti-Solute Carrier Family 6 Member 3 antibody Anti-SLC6A3 antibody Anti-DAT1 antibody

Information sourced from Uniprot.org

Model	Name	Host	Clonality	Reactivity	Application
STJ191449	Anti-SLC6A3 antibody (STJ191449)	Rabbit	Polyclonal	Human/Mouse/Rat	WB/ELISA
STJ117430	Anti-SLC6A3 antibody (1-100) (STJ117430)	Rabbit	Polyclonal	Human/Mouse/Rat	WB/IHC-P/IF/ICC/ELISA
STJ500735	Anti-SLC6A3 antibody (550-600) (STJ500735)	Rabbit	Polyclonal	Human/Mouse/Rat	ELISA/IHC/IP/WB
STJA0041365	Anti-C-Raf antibody (C-Term) (STJA0041365)	Rabbit	Polyclonal	Human/Mouse/Rat	ELISA/WB
STJA0025177	Anti-Recombinant-SLC6A3 antibody [RM2C05] (STJA0025177)	Rabbit	Monoclonal	Human	FC/IP/WB

Anti-SLC6A3 antibody (C-Term) (STJA0003616)

General Information