Anti-SLC6A2 antibody (5-85 aa) (STJ13102216)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from aa region 5-85 of human SLC6A2 conjugated to an immunogenic carrier protein was used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-SLC6A2 (5-85 aa) for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB (confirmed by recombinant protein). A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | SLC6A2 |
| Gene ID | 6530 |
| Uniprot ID | SC6A2_HUMAN |
| Immunogen | A synthetic peptide from aa region 5-85 of human SLC6A2 conjugated to an immunogenic carrier protein was used as the antigen. |
| Immunogen Region | 5-85 aa |
| Specificity | Specific for SLC6A2. |
Additional Info
| Function | Mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline), the primary signaling neurotransmitter in the autonomic sympathetic nervous system. Is responsible for norepinephrine re-uptake and clearance from the synaptic cleft, thus playing a crucial role in norepinephrine inactivation and homeostasis. Can also mediate sodium- and chloride-dependent transport of dopamine. |
| Protein Name | Sodium-Dependent Noradrenaline TransporterNorepinephrine TransporterNetSolute Carrier Family 6 Member 2 |
| Database Links | Reactome: R-HSA-442660Reactome: R-HSA-5619109 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCell ProjectionAxonSynapseSynaptosome |
| Alternative Antibody Names | Anti-Sodium-Dependent Noradrenaline Transporter antibodyAnti-Norepinephrine Transporter antibodyAnti-Net antibodyAnti-Solute Carrier Family 6 Member 2 antibodyAnti-SLC6A2 antibodyAnti-NAT1 antibodyAnti-NET1 antibodyAnti-SLC6A5 antibody |
Information sourced from Uniprot.org