| Tissue Specificity | Almost exclusively expressed in the brain. |
| Function | Functions as a sodium-dependent neutral amino acid transporter. Exhibits preference for the branched-chain amino acids, particularly leucine, valine and isoleucine and methionine. Can also transport low-affinity substrates such as alanine, phenylalanine, glutamine and pipecolic acid. Mediates the saturable, pH-sensitive and electrogenic cotransport of proline and sodium ions with a stoichiometry of 1:1. May have a role as transporter for neurotransmitter precursors into neurons. In contrast to other members of the neurotransmitter transporter family, does not appear to be chloride-dependent. |
| Protein Name | Sodium-Dependent Neutral Amino Acid Transporter B(0at2Sodium- And Chloride-Dependent Neurotransmitter Transporter Ntt73Sodium-Coupled Branched-Chain Amino-Acid Transporter 1Solute Carrier Family 6 Member 15Transporter V7-3 |
| Database Links | Reactome: R-HSA-352230Reactome: R-HSA-442660 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Sodium-Dependent Neutral Amino Acid Transporter B(0at2 antibodyAnti-Sodium- And Chloride-Dependent Neurotransmitter Transporter Ntt73 antibodyAnti-Sodium-Coupled Branched-Chain Amino-Acid Transporter 1 antibodyAnti-Solute Carrier Family 6 Member 15 antibodyAnti-Transporter V7-3 antibodyAnti-SLC6A15 antibodyAnti-B0AT2 antibodyAnti-NTT73 antibodyAnti-SBAT1 antibody |
Information sourced from Uniprot.org
