| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SLC6A15 (350-450) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC6A15 |
| Gene ID: |
55117 |
| Uniprot ID: |
S6A15_HUMAN |
| Immunogen Region: |
350-450 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 350-450 of human SLC6A15 (NP_877499.1). |
| Immunogen Sequence: |
LVVFAVLGFKANVINEKCIT QNSETIMKFLKMGNISQDII PHHINLSTVTAEDYHLVYDI IQKVKEEEFPALHLNSCKIE EELNKAVQGTGLAFIAFTEA M |
| Tissue Specificity | Almost exclusively expressed in the brain. |
| Function | Functions as a sodium-dependent neutral amino acid transporter. Exhibits preference for the branched-chain amino acids, particularly leucine, valine and isoleucine and methionine. Can also transport low-affinity substrates such as alanine, phenylalanine, glutamine and pipecolic acid. Mediates the saturable, pH-sensitive and electrogenic cotransport of proline and sodium ions with a stoichiometry of 1:1. May have a role as transporter for neurotransmitter precursors into neurons. In contrast to other members of the neurotransmitter transporter family, does not appear to be chloride-dependent. |
| Protein Name | Sodium-Dependent Neutral Amino Acid Transporter B(0at2Sodium- And Chloride-Dependent Neurotransmitter Transporter Ntt73Sodium-Coupled Branched-Chain Amino-Acid Transporter 1Solute Carrier Family 6 Member 15Transporter V7-3 |
| Database Links | Reactome: R-HSA-352230Reactome: R-HSA-442660 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Sodium-Dependent Neutral Amino Acid Transporter B(0at2 antibodyAnti-Sodium- And Chloride-Dependent Neurotransmitter Transporter Ntt73 antibodyAnti-Sodium-Coupled Branched-Chain Amino-Acid Transporter 1 antibodyAnti-Solute Carrier Family 6 Member 15 antibodyAnti-Transporter V7-3 antibodyAnti-SLC6A15 antibodyAnti-B0AT2 antibodyAnti-NTT73 antibodyAnti-SBAT1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
