| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SLC6A15 |
| Gene ID: | 55117 |
| Uniprot ID: | S6A15_HUMAN |
| Immunogen Region: | 350-450 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 350-450 of human SLC6A15 (NP_877499.1). |
| Immunogen Sequence: | LVVFAVLGFKANVINEKCIT QNSETIMKFLKMGNISQDII PHHINLSTVTAEDYHLVYDI IQKVKEEEFPALHLNSCKIE EELNKAVQGTGLAFIAFTEA M |
| Tissue Specificity | Almost exclusively expressed in the brain. |
| Function | Functions as a sodium-dependent neutral amino acid transporter. Exhibits preference for the branched-chain amino acids, particularly leucine, valine and isoleucine and methionine. Can also transport low-affinity substrates such as alanine, phenylalanine, glutamine and pipecolic acid. Mediates the saturable, pH-sensitive and electrogenic cotransport of proline and sodium ions with a stoichiometry of 1:1. May have a role as transporter for neurotransmitter precursors into neurons. In contrast to other members of the neurotransmitter transporter family, does not appear to be chloride-dependent. |
| Protein Name | Sodium-Dependent Neutral Amino Acid Transporter B(0at2 Sodium- And Chloride-Dependent Neurotransmitter Transporter Ntt73 Sodium-Coupled Branched-Chain Amino-Acid Transporter 1 Solute Carrier Family 6 Member 15 Transporter V7-3 |
| Database Links | Reactome: R-HSA-352230 Reactome: R-HSA-442660 |
| Cellular Localisation | Membrane Multi-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Sodium-Dependent Neutral Amino Acid Transporter B(0at2 antibody Anti-Sodium- And Chloride-Dependent Neurotransmitter Transporter Ntt73 antibody Anti-Sodium-Coupled Branched-Chain Amino-Acid Transporter 1 antibody Anti-Solute Carrier Family 6 Member 15 antibody Anti-Transporter V7-3 antibody Anti-SLC6A15 antibody Anti-B0AT2 antibody Anti-NTT73 antibody Anti-SBAT1 antibody |
Information sourced from Uniprot.org