Anti-SLC5A5 antibody (544-643) (STJ113663)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SLC5A5 (544-643) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC5A5 |
| Gene ID | 6528 |
| Uniprot ID | SC5A5_HUMAN |
| Immunogen Region | 544-643 |
| Immunogen Sequence | ALISCLTGPTKRSTLAPGLL WWDLARQTASVAPKEEVAIL DDNLVKGPEELPTGNKKPPG FLPTNEDRLFFLGQKELEGA GSWTPCVGHDGGRDQQETNL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 544-643 of human SLC5A5 (NP_000444.1). |
Additional Info
| Tissue Specificity | Expression is primarily in thyroid tissue, but also to a lower extent in mammary gland and ovary. Expression is reduced in tumors. |
| Post Translational Modifications | Glycosylated. |
| Function | Sodium:iodide symporter that mediates the transport of iodide into the thyroid gland. Can also mediate the transport of chlorate, thiocynate, nitrate and selenocynate. |
| Protein Name | Sodium/Iodide CotransporterNa(+/I(- CotransporterNatrium Iodide TransporterSodium-Iodide SymporterNa(+/I(- SymporterSolute Carrier Family 5 Member 5 |
| Database Links | Reactome: R-HSA-209968Reactome: R-HSA-428643Reactome: R-HSA-5619096 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCytoplasm |
| Alternative Antibody Names | Anti-Sodium/Iodide Cotransporter antibodyAnti-Na(+/I(- Cotransporter antibodyAnti-Natrium Iodide Transporter antibodyAnti-Sodium-Iodide Symporter antibodyAnti-Na(+/I(- Symporter antibodyAnti-Solute Carrier Family 5 Member 5 antibodyAnti-SLC5A5 antibodyAnti-NIS antibody |
Information sourced from Uniprot.org