Anti-SLC5A10 antibody (STJA0009240)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human SLC5A10
General Information
| Short Description | Rabbit polyclonal anti-Sodium/mannose cotransporter SLC5A10/glucose cotransporter 5 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC5A10 |
| Gene ID | 125206 |
| Uniprot ID | SC5AA_HUMAN |
| Immunogen | Synthesized peptide derived from human SLC5A10 |
| Specificity | This antibody detects endogenous levels of SLC5A10 at Human, Mouse |
Additional Info
| Function | Isoform 1: Electrogenic Na+-coupled sugar symporter that actively transports D-mannose or D-fructose at the plasma membrane, with a Na+ to sugar coupling ratio of 1:1. Transporter activity is driven by a transmembrane Na+ electrochemical gradient set by the Na+/K+ pump. Exclusively recognizes sugar substrates having a pyranose ring with an axial hydroxyl group on carbon 2. Has likely evolved to enable renal reabsorption of D-mannose, an important constituent of oligosaccharide chains of glycoproteins. Contributes to dietary D-fructose reabsorption from glomerular filtrate across the brush border of the kidney. Isoform 2: Appears to have no transporter activity. |
| Protein Name | Sodium/Mannose Cotransporter Slc5a10Sodium/Glucose Cotransporter 5Na(+/Glucose Cotransporter 5Solute Carrier Family 5 Member 10 |
| Database Links | Reactome: R-HSA-189200 |
| Cellular Localisation | Apical Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Sodium/Mannose Cotransporter Slc5a10 antibodyAnti-Sodium/Glucose Cotransporter 5 antibodyAnti-Na(+/Glucose Cotransporter 5 antibodyAnti-Solute Carrier Family 5 Member 10 antibodyAnti-SLC5A10 antibodyAnti-SGLT5 antibody |
Information sourced from Uniprot.org