Anti-SLC4A2 antibody (830-910 aa) (STJ190551)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 830-910
General Information
| Short Description | Rabbit polyclonal anti-Anion exchange protein 2 (830-910 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC4A2 |
| Gene ID | 6522 |
| Uniprot ID | B3A2_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 830-910 |
| Immunogen Region | 830-910 aa |
| Specificity | B3A2 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Sodium-independent anion exchanger which mediates the electroneutral exchange of chloride for bicarbonate ions across the cell membrane. Plays an important role in osteoclast differentiation and function. Regulates bone resorption and calpain-dependent actin cytoskeleton organization in osteoclasts via anion exchange-dependent control of pH. Essential for intracellular pH regulation in CD8(+) T-cells upon CD3 stimulation, modulating CD8(+) T-cell responses. |
| Protein Name | Anion Exchange Protein 2Ae 2Anion Exchanger 2Non-Erythroid Band 3-Like ProteinBnd3lSolute Carrier Family 4 Member 2 |
| Database Links | Reactome: R-HSA-425381 |
| Cellular Localisation | Isoform A: Apical Cell MembraneMulti-Pass Membrane ProteinBasolateral Cell MembraneIsoform B1: Apical Cell MembraneIsoform B2: Apical Cell Membrane |
| Alternative Antibody Names | Anti-Anion Exchange Protein 2 antibodyAnti-Ae 2 antibodyAnti-Anion Exchanger 2 antibodyAnti-Non-Erythroid Band 3-Like Protein antibodyAnti-Bnd3l antibodyAnti-Solute Carrier Family 4 Member 2 antibodyAnti-SLC4A2 antibodyAnti-AE2 antibodyAnti-EPB3L1 antibodyAnti-HKB3 antibodyAnti-MPB3L antibody |
Information sourced from Uniprot.org