Anti-SLC4A1 antibody (STJ13100062)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from mouse Band 3 anion transport protein (SLC4A1, CD233) conjugated to blue carrier protein was used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-SLC4A1 for use in IHC and WB in Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1: 3000 is recommended for WB and 1:1000 for IHC-P. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20ยฐC for long term storage and refrigerated at 2-8ยฐC for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | Slc4a1 |
| Gene ID | 20533 |
| Uniprot ID | B3AT_MOUSE |
| Immunogen | A synthetic peptide from mouse Band 3 anion transport protein (SLC4A1, CD233) conjugated to blue carrier protein was used as the antigen. |
| Specificity | Specific for SLC4A1. |
Additional Info
| Function | Functions both as a transporter that mediates electroneutral anion exchange across the cell membrane and as a structural protein. Component of the ankyrin-1 complex of the erythrocyte membrane.required for normal flexibility and stability of the erythrocyte membrane and for normal erythrocyte shape via the interactions of its cytoplasmic domain with cytoskeletal proteins, glycolytic enzymes, and hemoglobin. Functions as a transporter that mediates the 1:1 exchange of inorganic anions across the erythrocyte membrane. Mediates chloride-bicarbonate exchange in the kidney, and is required for normal acidification of the urine. |
| Protein Name | Band 3 Anion Transport ProteinAnion Exchange Protein 1Ae 1Anion Exchanger 1Meb3Solute Carrier Family 4 Member 1Cd Antigen Cd233 |
| Database Links | Reactome: R-MMU-1237044Reactome: -MMU-1247673Reactome: -MMU-425381 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinBasolateral Cell MembraneDetected In The Erythrocyte Cell Membrane And On The Basolateral Membrane Of Alpha-Intercalated Cells In The Collecting Duct In The Kidney |
| Alternative Antibody Names | Anti-Band 3 Anion Transport Protein antibodyAnti-Anion Exchange Protein 1 antibodyAnti-Ae 1 antibodyAnti-Anion Exchanger 1 antibodyAnti-Meb3 antibodyAnti-Solute Carrier Family 4 Member 1 antibodyAnti-Cd Antigen Cd233 antibodyAnti-Slc4a1 antibodyAnti-Ae1 antibody |
Information sourced from Uniprot.org